October 03, 2014
by Sayer Ji
(GreenMedInfo.com) Long considered impossible to accomplish, new research reveals how a simple spice might contribute to the regeneration of the damaged brain.
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Turmeric is hands down one of the, if not the, most versatile healing spice in the world with over 600 experimentally confirmed health benefits, and an ancient history filled with deep reverence for its seemingly compassionate power to alleviate human suffering.
But, most of the focus over the past decade has been centered on only one of its many hundreds of phytocompounds: namely, the primary polyphenol in turmeric known as curcumin which gives the spice its richly golden hue. This curcumin-centric focus has lead to the development of some very good products, such as phospholipid bound curcumin concentrate (e.g. Meriva, BCM-95) which greatly helps to increase the absorption and bio-activity of curcumin. But, curcumin isolates are only capable of conferring a part of turmeric’s therapeutic power – and therein lies the limitation and hubris of the dominant ‘isolate the active ingredient’ model.
Indeed, it has become typical within the so-called nutraceutical industry to emulate the pharmaceutical model, which focuses on identifying a particular “monochemical” tree within the forest of complexity represented by each botanical agent, striving to standardize the delivery of each purported ‘active ingredient’ with each serving, as if it were a pharmaceutical drug. These extraction and isolation processes also generates proprietary formulas which are what manufacturers want to differentiate their product from all others and henceforth capture a larger part of the market share; a value proposition that serves the manufacturer and not the consumer/patient.
Truth be told, there is no singular ‘magic bullet’ in foods and herbs responsible for reproducing the whole plant’s healing power. There are, in fact, in most healing plants or foods hundreds of compounds orchestrated by the intelligent ‘invisible hand’ of God or ‘Nature,’ or whatever you wish to call it, and which can never be reduced to the activity of a singularly quantifiable phytocompound or chemical.
Beyond The Curcumin ‘Magic Bullet’ Meme
Now, an exciting new study published in the journal Stem Cell Research & Therapy provides additional support for the concept that curcumin alone is not enough to explain the healing power of turmeric as a whole plant. The study found that a little known, fat-soluble component within turmeric – Ar-tumerone – may make “a promising candidate to support regeneration in neurologic disease.”
Titled, “Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo,” German researchers evaluated the effects of this turmeric-derived compound on neural stem cells (NSCs) – the subgroup of brain cells capable of continuous self-renewal required for brain repair.
The study found that when brain cells were exposed to ar-tumerone, neural stem cells increased in number through enhanced proliferation. Moreover, these newly formed neural stem cells also increased the number of fully differentiated neuronal cells, indicating a healing effect was taking place. This effect was also observed in a live animal model, showing that rats injected with ar-tumerone into their brains experienced increases in neural stem cell proliferation and the creation of newly formed healthy brain cells.
This study did not go unnoticed by major medical news channels. Here are some good reviews if you wish to explore the implications in greater depth:
Newsweek: Curry Power: Turmeric Compound Boosts Growth of Brain’s Stem Cells
Guardian Liberty Voice: Turmeric Cure Evidence Grows
Monthly Prescribing Reference: Turmeric May Help Regenerate Brain Cells
Times of Malta: Turmeric Link to Brain Cell Repair
Medical Daily: Turmeric Helps Your Brain Heal Itself: Spice Up Your Brain
The GreenMedInfo.com Turmeric Database Confirms It’s Brain-Saving Power!
As you may already know, our database is the world’s most extensive open access natural medical database on over 1,800 different natural substances, with over 1600 study abstracts on turmeric’s healing properties indexed thus far: view the Turmeric research page here to view! If you take a look at the laundry list of over 600 diseases that this spice (or its components, e.g. curcumin) has been studied for to prevent and/or treat, the sheer volume of supportive literature is astounding. Amazingly, we have identified over 180 physiological pathways – according to their conventional pharmacological characterization, e.g. COX-2 inhibitor, Interleukin 6 down-regulator – by which turmeric or its components heals the human body. In addition, you will find over 100 articles on turmeric’s neuroprotective properties on this page: Turmeric as a Neuroprotective agent.